Diabetic retinopathy, also known as diabetic eye disease (DED), is a medical condition in which damage occurs to the retina due to diabetes mellitus. It is a leading cause of blindness in developed countries. Diabetic retinopathy affects up to eighty percentages of those who have had diabetes for twenty years or more. At least ninety percentage of new cases could be reduced with proper treatment and monitoring of the eyes The longer a person has diabetes, the higher his or her chances of developing diabetic retinopathy Each year in the United States, diabetic retinopathy accounts for twelve percentage of all new cases of blindness. It is also the leading cause of blindness in people aged twenty to sixty four year. Diabetic retinopathy often has no early warning signs. Even macular enema, which can cause rapid central vision loss, may not have any warning signs for some time. In general, however, a person with macular enema is likely to have blurred vision, making it hard to do things like read or drive. In some cases, the vision will get better or worse during the day.