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Neuroleptic for management of psychosis

Gudisa Bereda

Antipsychotic medications can support to make psychotic symptoms less intense and infrequent. High potency first generation antipsychotic medications such as haloperidol, thiothixene, and fluphenazine are highly binding to dopamine-2 receptors; they have higher efficacy, more extra pyramidal symptoms, and higher incidence of tardive dyskinesia, less cognitive problems such as less sedation and less cardiovascular side effects. Side effects of risperidone include elevations of serum prolactin; elevated prolactin levels can lead to amenorrhea, galactorrhea, gynecomastia, and sexual dysfunction. Mild to moderate weight gain and mild elevations in serum lipids and glucose may occur in risperidone usage. Risperidone also cause neuroleptic malignant syndrome, seizures, orthostatic hypotension, priapism, blurred vision.

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